01.1 - Graduação (Sede)
URI permanente desta comunidadehttps://arandu.ufrpe.br/handle/123456789/2
Navegar
5 resultados
Resultados da Pesquisa
Item Estudo da capacidade neutralizante do extrato hidroalcoólico de sementes de Stryphnodendron fissuratum Mart. (Leguminosa Mimosoideae) sobre a toxicidade da peçonha de Bothrops leucurus(2018-08-14) Silva, Renatta Priscilla Ferreira; Silva, Marliete Maria Soares da; http://lattes.cnpq.br/6064066939275575; http://lattes.cnpq.br/4036416150000631Accidents involving venomous snakes represent a significant public health issue, with approximately 2.5 million cases reported annually worldwide. The conventional treatment for such accidents is the administration of antivenom serum, which effectively neutralizes tissue damage but can cause significant side effects. In search of alternatives, studies have investigated the potential of plants with antivenom properties, often used by rural workers, as a complementary or alternative option to conventional treatment. Among the studied plants, species of the genus Stryphnodendron have stood out, especially Stryphnodendron fissuratum, found exclusively in Brazil. However, phytochemical information and knowledge about its biological properties are scarce. In this context, this study evaluated the extract of S. fissuratum seeds, investigating its chemical composition, potential phytotoxic effects on seedlings, and its ability to neutralize the enzymatic activities of the venom of the snake Bothrops leucurus, one of the most common in Brazil. For the experiment, S. fissuratum seeds were dried, ground, and subjected to an extraction process using an ethanol/water solution. Subsequently, this extract was tested on lettuce seedlings (Lactuca sativa), which were exposed to B. leucurus venom to assess phytotoxic and neutralization effects. The results showed that venom treatment did not affect seed germination but significantly reduced seedling growth. The S. fissuratum extract, in turn, reduced the enzymatic activities of the venom, including total proteases, trypsin, chymotrypsin, and phospholipases. In summary, the study demonstrated that the extract of S. fissuratum seeds has antivenom potential, capable of reducing the toxicity of B. leucurus venom in lettuce seedlings. Additionally, the presence of bioactive compounds in the extract was identified, which could be explored in the development of new therapies against venomous snake accidents.Item Levantamento e classificação da toxicidade das plantas ornamentais presentes nos parques urbanos de Recife - Pernambuco(2023-05-02) Zelaquett, Danilo de Souza; Brasileiro, Hélida Maria de Lima Maranhão; http://lattes.cnpq.br/4735569144086617; http://lattes.cnpq.br/2587653841058709The presence of green areas in urban centers is essential for the well-being of the population, but many ornamental plants can be toxic. The toxic agents of plants are linked to their secondary metabolism such as oxalates, saponins, alkaloids, glycosides and terpenes. Although the number of cases of plant poisoning is small, children are the most expected. The objective of this study was to carry out a survey of toxic ornamental plants present in 07 urban parks in Recife, capital of Pernambuco, and classify them according to their degree of toxicity. For this, instruments were used to collect information and record images, taxonomic identification, classification of the degree of toxicity, description of the part of the plant related to poisoning and prevalent toxic metabolites. In the parks, 29 species of toxic ornamental plants were identified, belonging to 12 botanical families, of which species from the families Apocynaceae, Araceae and Euphorbiaceae totaled 52%. The species Mangifera indica, Sansevieria trifasciata, Plumeria rubra and Thaumatophyllum bipinnatifidum were the most common, while the plants with the highest degree of toxicity found in the parks were Duranta erecta, Lantana camara, Nerium oleander and Thevetia peruviana. In all the evaluated parks, toxic plants were found near the recreation and food areas, most of the time unidentified, and with free access to the population and animals. Thus, it is necessary that the choice of species used consider their toxic potential, that more studies are careful and that educational activities are implemented for population knowledge and the adoption of preventive measures for accidents.Item Uso de plantas tóxicas na arborização e ornamentação urbana e suas ameaças à saúde pública e polinizadores locais(2021-12-14) Gomes, Nicole Pegoraro; Sperandio, Marcus Vinícius Loss; http://lattes.cnpq.br/4157291425794314; http://lattes.cnpq.br/5024205327901053The use of toxic plants along an evolutionary journey encompasses different forms and functions in different cultures around the world as resources of the time. Currently, it can be said that the presence of harmful species in areas of urban afforestation and ornamentation results in toxicological accidents to the population and damage to the ecology of cities. Based on this statement, because of the impacts reflected on public health and the integrity of pollinators inhabiting an urban gradient, this study aims to prepare a bibliographic survey on the use of toxic plants over time, alluding to the targeted species’ urban ornamentation and its threats, as well as promoting dissemination strategies, and technical and scientific recommendations aimed at the population and the municipal government. A search was then carried out using articles and dissertations present in specific databases: Google Scholar, Science Direct, Scientific Electronic Library Online (SciELO), PubMed, National System of Toxic-Pharmacological Information (SINITOX), National Agency of Health Surveillance (ANVISA) and specialized periodicals. Pedagogical and scientific dissemination activities were carried out using articles and dissertations present in specific databases: Google Scholar, Science Direct, Scientific Electronic Library Online (SciELO), PubMed, National System of Toxic-Pharmacological Information (SINITOX), National Agency of Health Surveillance (ANVISA) and specialized periodicals. Pedagogical and scientific dissemination activities were carried out at the Recife Botanical Garden. With the support of the institution, a proposal for a technical-scientific recommendation was drawn up to implement municipal policies focused on the central theme. Insights from the study highlighted that the biodiversity of cities becomes scarcer, and the population more susceptible to poisoning, due to gaps in urban afforestation plans, failures in the construction of current public health policies, and little investment in environmental education for the population covering harmful species. As a result of these observations, it is evident that species that present toxic characteristics related to either their bark, latex, flowers, or leaves, should not be utilized as a first choice in afforestation and urban ornamentation of public areas. Toxic plants would still not be recommended due to the potential contact with the population and their interference in the ecosystem of fauna pollinators.Item Relatório de Estágio Supervisionado Obrigatório (ESO) realizado no Laboratório de Ecofisiologia e Comportamento Animal (LECA-UFRPE), Recife-PE(2019-01-25) Chaves, Hisadora Advincula da Silva; Mendonça, Fábio de Souza; http://lattes.cnpq.br/1976344298387988; http://lattes.cnpq.br/1849357038300502Due to the importance of the veterinarian in zebrafish (Danio rerio) vivarium, the Estágio Supervisionado Obrigatório (ESO) was carried out during the period from September 20 to December 07, 2018, in the Laboratório de Ecofisiologia e Comportamento Animal (LECA) of the Departamento de Morfologia e Fisiologia Animal (DMFA) of the Universidade Federal Rural de Pernambuco (UFRPE) in Dois Irmãos, Recife, Pernambuco, Brazil. The report was divided into Chapter I, describing the stage entity and the activities developed, depicting the training developed at the stage, and Chapter II, which represents the experiment performed. Zebrafish has become internationally recognized as an experimental model for evaluating acute and chronic toxicity tests caused by chemical products in scientific research in recent decades. Serjania glabrata Kunth is a plant present in the Caatinga biome widely distributed in the Semiarid region of Northeastern Brazil and has been reported as toxic to goats by producers. Thus, this study aimed to evaluate the toxic effects of the ethanolic extract of the leaves of Serjania glabrata Kunth on zebrafish embryos (Danio rerio). The leaves of S. glabrata Kunth were collected in the county of Salgado de São Félix-PB and, from these, the ethanolic extract diluted in 1% dimethylsulfoxide with a concentration of 5 mg/mL was obtained. The parameters evaluated were heart rate, mortality and teratogenic effects, such as column and tail deformation, pericardial and vitelline sac edema, and coagulation, at 24, 48, 72 and 96 hours post fertilization intervals under an optical microscope. The concentrations of 10, 100 and 1000 μg/L did not cause teratogenic effects, as well as mortality, but caused alterations in heart rate.Item Surtos de fotossensibilização primária associada ao consumo de Froelichia humboldtiana (Amaranthaceae) no Agreste Pernambucano – Relato de caso(2018-08-22) Silva Filho, Givaldo Bom da; Mendonça, Fábio de Souza; http://lattes.cnpq.br/1976344298387988; http://lattes.cnpq.br/4002013072191039