Bacharelado em Ciências Biológicas (Sede)
URI permanente desta comunidadehttps://arandu.ufrpe.br/handle/123456789/5
Siglas das Coleções:
APP - Artigo Publicado em Periódico
TAE - Trabalho Apresentado em Evento
TCC - Trabalho de Conclusão de Curso
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2 resultados
Resultados da Pesquisa
Item Concentração de elementos-traço chumbo (Pb) e cobre (Cu) em tecidos de Chelonia mydas (Linnaeus, 1758) no Litoral Sul de Pernambuco, Nordeste do Brasil(2021-08-06) Queiroz, Emily Pereira de; Moura, Geraldo Jorge Barbosa de; Rodrigues, Midiã da Silva; http://lattes.cnpq.br/4953311636839935; http://lattes.cnpq.br/1348666346504103; http://lattes.cnpq.br/9237498056744804Between threats to sea turtles species is the contamination of marine enviroments caused by trace elements wich infiltrate into organisms through food, airways or skin and can be passed on by trophic levels. The species Chelonia mydas has coastal habits whose main diet item is seaweed, which had evidence of accumulation by trace elements. This work determined the concentrations of trace elements lead (Pb) and copper (Cu), in order to know the level of contamination of local individuals and the bioavailability of the elements in habitat. 43 samples of C. mydas liver and muscle organs from the southern coast of Pernambuco, Northeast Brazil, collected from November 2016 to November 2018 were used. The quantification was performed by an Inductively coupled plasma - optical emission spectrometry (ICP OES). Cu showed a greater amount in liver, while Pb was present in a higher concentration in muscle, not being detectable in liver. For Cu, the highest concentration found was 64,683 mg kg-1 (6,389–212,286) while for Pb it was 4,115mg kg-1 (1.4–7,424). The southern coast of Pernambuco showed higher concentrations than other Brazilian states and several areas around the world, showing how other threats to the species mask the impacts of these contaminants, whose accumulation mechanisms need further studies to be fully understood. The values found provide a basis for monitoring the species and contamination of the local habitat.Item Avaliação da cafeína no controle da infecção experimental de macrófago por Salmonella typhimurium(2019) Almeida, Ingrydt de Alcântara; Lima Filho, José Vitor Moreira; Tavares, Lethicia Souza; http://lattes.cnpq.br/4128808335995892; http://lattes.cnpq.br/9476972124107533; http://lattes.cnpq.br/6015462685217823Salmonellosis is an infectious disease transmitted mainly by foods contaminated with bacteria of the genus Salmonella, among them Salmonella enterica serotype Typhimurium, which can cause gastroenteritis until sepsis and septic shock in groups at risk. Organic compounds for pharmacological purposes are being increasingly tested. Among these compounds, caffeine (1,3,7-trimethylxanthine), one of the most used pharmacological and psychostimulant substances in the world. Severalstudies have demonstrated its role as a therapeutic adjunct, immunomodulator and adenosine receptor antagonist (ARs). In view of this, the objective was to evaluate the immunomodulatory potential of caffeine in peritoneal macrophages infected with Salmonella enterica Sor. Typhimurium. For this, in vitro tests were performed with cultures of macrophages exposed to caffeine concentrations to determine the degree of cytotoxicity of the compound; curative and preventive tests of cell viability, in order to evaluate cellular survival and quantification of intracellular bacteria, aiming to analyze the clearance of the pathogen from the intracellular medium. A direct antibacterial activity test was also carried out to evaluate the efficacy of caffeine in preventing the development of S. typhimurium. The results demonstrated that caffeine did not produce a toxic effect on the uninfected macrophages at the concentrations used, promoted a greater viability of the infected macrophages, but was not able to act as a direct bactericide. Caffeine contributed to the survival of macrophages infected with S. Typhimurium, having potential for the control of bacterial infections.